Branded pharma sector includes companies whose drugs are patented and in the commercial stage. These companies comprise 69% (valuation of $3.6 trillion) of the value of the entire pharma industry  and generated over $700 billion in revenue in 2019.

The most valuable companies in cardiometabolic care are Eli Lilly and Novo Nordisk. Biogen, UCB and Otsuka are leader in Cerntral Nervous System (CNS) disease care. Valuable companies in dermatology are Galderma, Pierre Fabre, LEO Pharma, Merz and Maruho. Pfizer, Merck and Roche are the clauable companies in oncology. Takeda and Vertex lead in rare disease segment.

See the full list of Top 1000 Pharmaceutical Companies below.


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  • The Global Pharmaceutical Industry
  • Rapid Growth of Biotech Sector
  • The Evolving Branded Pharma Sector
  • The Generic Pharma Sector
  • Top 1000 Companies by Value
  • Profiles of the Top 500 Companies


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List of Top 1000 Pharmaceutical Companies by Value

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Value

Name

Headquarters

Value Estimate

Revenue

Rank  Location (Sep 2020) (Trailing)
2020
1 Roche Basel, Switzerland $328 bn $49 bn
2 Janssen (J&J) Raritan, NJ, US $279 bn $42 bn
3 Pfizer New York Area, US $257 bn $49 bn
4 AbbVie Chicago Area $242 bn $36 bn
5 Merck New York Area, US $233 bn $47 bn
6 Novartis Basel, Switzerland $210 bn $49 bn
7 Amgen Thousand Oaks, CA, US $164 bn $24 bn
8 AstraZeneca Boston Area, US $162 bn $25 bn
9 Bristol-Myers Squibb New York Area, US $158 bn $34 bn
10 Novo Nordisk Copenhagen, Denmark $155 bn $19 bn
11 Eli Lilly Indiana, US $151 bn $22 bn
12 Boehringer Ingelheim Ingelheim, Germany $148 bn $22 bn
13 GlaxoSmithKline London, United Kingdom $136 bn $43 bn
14 Bayer Leverkusen, Germany $133 bn $20 bn
15 Sanofi Paris, France $120 bn $42 bn
16 Takeda Tokyo Japan $104 bn $30 bn
17 CSL Parkville, Australia $100 bn $9 bn
18 Gilead Bay Area, US $87 bn $22 bn
19 Zoetis New York Area, US $82 bn $6.3 bn
20 Chugai Tokyo, Japan $72 bn $6.8 bn
21 Hengrui Medicine Jiangsu Province, China $69 bn $3.4 bn
22 Vertex Pharma Boston Area, US $65 bn $5.4 bn
23 Regeneron New York Area, US $58 bn $8.6 bn
24 Daiichi Sankyo Tokyo, Japan $54 bn $8.9 bn
25 Merck KGaA Pharma Berlin, Germany $50 bn $7.5 bn
26 Biogen Boston Area, US $48 bn $14 bn
27 Yangtze River Pharma Jiangsu Province, China $44 bn $12 bn
28 Servier Paris, France $36 bn $5.4 bn
29 Teva Israel $35 bn $16 bn
30 Celltrion South Korea $33 bn $1.2 bn
31 CSPC Pharma Hebei Province, China $33 bn $5 bn
32 Zhifei Bio Sichuan Province, China $31 bn $1.7 bn
33 Seattle Genetics Seattle, US $30 bn $1 bn
34 Menarini Florence, Italy $30 bn $4.4 bn
35 Bausch Health New York Area, US $29 bn $8.1 bn
36 Royalty Pharma New York Area, US $29 bn $1.9 bn
37 Hansoh Pharma Lianyungang, China $26 bn $1.1 bn
38 Astellas Tokyo, Japan $26 bn $11 bn
39 Grifols Barcelona, Spain $26 bn $6 bn
40 Alexion New York Area, US $25 bn $5.5 bn
41 Eisai Tokyo, Japan $24 bn $6.5 bn
42 Moderna Boston Area, US $24 bn $105 mn
43 Qilu Pharma Shandong Province, China $24 bn $3.6 bn
44 UCB Brussels, Belgium $24 bn $5.8 bn
45 Sino Biopharma Hong Kong $23 bn $3.4 bn
46 Changchun Tech Jilin Province, China $23 bn $1.1 bn
47 Genmab Copenhagen, Denmark $22 bn $1.5 bn
48 Otsuka Tokyo, Japan $22 bn $13 bn
49 Pientzehuang Pharma Fujian Province, China $22 bn $859 mn
50 Kelun Group Sichuan Province, China $22 bn $6 bn
51 Galderma La Tour-de-Peilz, Switzerland $20 bn $3 bn
52 BeiGene Beijing, China $20 bn $224 mn
53 Mylan Pittsburgh Area, US $20 bn $11 bn
54 Jemincare Jianxi Province, China $19.3 bn $5.3 bn
55 Pierre Fabre Paris, France $18.7 bn $2.8 bn
56 Immunomedics New York Area, US $18.6 bn $20 mn
57 Incyte Philadelphia Area, US $18.5 bn $2.3 bn
58 Horizon Therapeutics Chicago Area $17.9 bn $1.5 bn
59 Yunnan Baiyao Yunnan Province, China $17.6 bn $4.4 bn
60 Kangtai Bio Guangdong Province, China $17.3 bn $283 mn
61 Octapharma Lachen, Switzerland $17.1 bn $2.5 bn
62 Fosun Pharma Shanghai, China $16.7 bn $4 bn
63 Ferring Geneva, Switzerland $16.7 bn $2.5 bn
64 Sun Pharma Mumbai, India $16.4 bn $4.2 bn
65 Abbott EPD Chicago Area $16.1 bn $4.4 bn
66 Chiesi Parma, Italy $15.5 bn $2.3 bn
67 BioNTech Mainz, Germany $15.4 bn $141 mn
68 Ono Osaka, Japan $14.7 bn $2.7 bn
69 BioMarin Bay Area, US $13.8 bn $1.8 bn
70 Alnylam Boston Area, US $13.5 bn $345 mn
71 Elanco Indiana, US $13.4 bn $2.8 bn
72 Shionogi Osaka, Japan $13.3 bn $3 bn
73 Mundipharma New York Area, US $13.2 bn $2 bn
74 Hualan Bio Henan Province, China $13.1 bn $521 mn
75 NC Pharma / EMS Hortolandia, Brazil $12.8 bn $1.9 bn
76 Fresenius Kabi Segment Hessen, Germany $12.5 bn $3.4 bn
77 Walvax Yunnan Province, China $12.5 bn $169 mn
78 Samumed San Diego, CA $12.4 bn NA
79 Kyowa Kirin Tokyo, Japan $12.2 bn $2.8 bn
80 Recordati Milan, Italy $12.2 bn $1.6 bn
81 Shanghai Pharma – Mfg Shanghai, China $12.1 bn $3.3 bn
82 Tianjin Pharma Tianjin, China $12 bn $3.3 bn
83 R-Pharm Moscow, Russia $11.9 bn $1.8 bn
84 Grupo Insud Madrid, Spain $11.7 bn $1.7 bn
85 Adimab Lebanon, NH, US $11.4 bn NA
86 LEO Pharma Copenhagen, Denmark $11.4 bn $1.7 bn
87 SK Biopharma Seoul, Korea $11 bn $5.2 mn
88 Grunenthal Aachen, Germany $10.9 bn $1.6 bn
89 Roemmers Argentina $10.8 bn $3 bn
90 Innovent Biologics Jiangsu Province, China $10.5 bn $238 mn
91 Vifor Pharma St. Gallen, Switzerland $10.2 bn $2 bn
92 Bracco Milan, Italy $10.1 bn $1.5 bn
93 Dr. Reddy’s Hyderabad, India $10.1 bn $2.3 bn
94 Junshi Biosciences Jiangsu Province, China $10 bn $147 mn
95 Ibsen Paris, France $10 bn $3 bn
96 Roivant Sciences New York Area, US $10 bn NA
97 Sarepta Therapeutics Boston Area, US $9.9 bn $450 mn
98 Harbin Pharma Heilongjiang Province, China $9.7 bn $2.7 bn
99 CureVac Tubingen, Germany $9.6 bn $19 mn
100 Ceva Sante Animale Dusseldorf, Germany $9.3 bn $1.4 bn
101 Neurocrine Biosciences San Diego, US $9.3 bn $1 bn
102 Gan & Lee Pharma Beijing, China $9.3 bn $445 mn
103 argenx Netherlands $8.8 bn $70 mn
104 Humanwell Healthcare Hubei Province, China $8.8 bn $2.9 bn
105 Sobi Sweden $8.7 bn $1.6 bn
106 CR Pharma Rx Segment Hong Kong $8.6 bn $4.3 bn
107 Hetero Drugs Hyderabad, India $8.6 bn $2.3 bn
108 Merz Hessen, Germany $8.5 bn $1.2 bn
109 Hikma London, United Kingdom $8.4 bn $2.2 bn
110 Kangmei Pharma Guangdong Province, China $8.4 bn $825 mn
111 Jazz Pharma Bay Area, US $8.4 bn $2.2 bn
112 Huahai Pharma Zhejiang Province, China $8.4 bn $855 mn
113 Cipla Mumbai, India $8.3 bn $2.3 bn
114 Serum Institute of India Pune, India $8.3 bn $819 mn
115 Baxter Pharma Chicago Area $8.2 bn $2.2 bn
116 Shanghai RAAS Shanghai, China $8.2 bn $367 mn
117 CanSino Biologics Tianjin, China $8.2 bn $2.2 mn
118 Alfasigma Florence, Italy $8.2 bn $1.2 bn
119 Mitsubishi Tanabe Osaka, Japan $8 bn $3.8 bn
120 Lundbeck Copenhagen, Denmark $7.8 bn $2.6 bn
121 Tiantan Biological Beijing, China $7.5 bn $463 mn
122 Endo International New York Area, US $7.3 bn $3 bn
123 Biocon Bangalore, India $7.3 bn $871 mn
124 Torrent Pharma Ahmedabad, India $7.3 bn $1 bn
125 Apotex Toronto Area, Canada $7.3 bn $2 bn
126 STADA Bad Vilbel, Germany $7.2 bn $3.1 bn
127 Ascendis Pharma Copenhagen, Denmark $7.1 bn $9.4 mn
128 Santen Osaka, Japan $7.1 bn $2.2 bn
129 Angelini Rome, Italy $7 bn $1 bn
130 Schwabe Stutensee, Germany $7 bn $1 bn
131 Aurobindo Hyderabad, India $6.9 bn $3.1 bn
132 Betta Pharm Zhejiang Province, China $6.8 bn $246 mn
133 Intas Pharma Ahmedabad, India $6.6 bn $1.8 bn
134 Exelixis Bay Area, US $6.6 bn $998 mn
135 Ache Laboratorios Guarulhos, Brazil $6.6 bn $1 bn
136 Unilab Philippines $6.6 bn $1 bn
137 Dainippon Sumitomo Osaka, Japan $6.6 bn $4.6 bn
138 Orion Finland $6.5 bn $1.2 bn
139 Lupin Mumbai, India $6.4 bn $1.9 bn
140 Huadong Medicine Zhejiang Province, China $6.4 bn $4.7 bn
141 Mirati Therapeutics San Diego, US $6.4 bn $1.7 mn
142 Zydus Cadila Ahmedabad, India $6.3 bn $1.9 bn
143 Kedrion Florence, Italy $6.3 bn $953 mn
144 King-Friend Bio Jiangsu Province, China $6.2 bn $380 mn
145 Shin Poong South Korea $6.2 bn $164 mn
146 lonis San Diego, US $6.1 bn $940 mn
147 Emergent BioSolutions Gaithersburg, MD, US $6 bn $1.2 bn
148 Green Valley Pharma Shanghai, China $5.9 bn $900 mn
149 Guangzhou Pharma Guangdong Province, China $5.9 bn $8.7 bn
150 MyoKardia Bay Area, US $5.9 bn NA
151 Momenta Boston Area, US $5.8 bn $30 mn
152 Kanghong Pharma Sichuan Province, China $5.8 bn $443 mn
153 Acceleron Boston Area, US $5.7 bn $87 mn
154 Novavax Gaithersburg, MD, US $5.7 bn $50 mn
155 Aspen Pharmacare South Africa $5.7 bn $2.2 bn
156 Italfarmaco Milan, Italy $5.7 bn $856 mn
157 Zambon Milan, Italy $5.6 bn $853 mn
158 Maruho Osaka, Japan $5.6 bn $847 mn
159 ACADIA Pharma San Diego, US $5.5 bn $393 mn
160 Zai Lab Shanghai China $5.5 bn $28 mn
161 Youcare Pharma Beijing, China $5.4 bn $1.5 bn
162 Salubris Pharma Guangdong Province, China $5.4 bn $516 mn
163 Nippon Shinyaku Tokyo, Japan $5.2 bn $1.1 bn
164 Grupo Ferrer Barcelona, Spain $5.2 bn $790 mn
165 Yifan Pharma Zhejiang Province, China $5.1 bn $775 mn
166 CRISPR Therapeutics Zug, Switzerland $5.1 bn $289 mn
167 PeptiDream Kawasaki, Japan $5.1 bn $0 mn
168 Livzon Guangdong Province, China $5 bn $1.3 bn
169 ALTEOGEN South Korea $5 bn $36 mn
170 Tasly Pharma Tianjin, China $5 bn $2.5 bn
171 Alkem Mumbai, India $4.8 bn $1.1 bn
172 Kalbe North Sumatra, Indonesia $4.8 bn $1.5 bn
173 Dechra Pharma Northern UK $4.7 bn $637 mn
174 Mallinckrodt London, United Kingdom $4.5 bn $2.3 bn
175 Chi-Med Hong Kong $4.5 bn $209 mn
176 Laboratoires Thea Clermont-Ferrand, France $4.5 bn $678 mn
177 lovance Bay Area, US $4.5 bn NA
178 Samsung Bioepis South Korea $4.4 bn $850 mn
179 Wolwo Pharma Zhejiang Province, China $4.4 bn $88 mn
180 Dongbao Pharma Jilin Province, China $4.4 bn $398 mn
181 Buchang Pharma Shandong Province, China $4.4 bn $2.1 bn
182 Mega Pharma Uruguay $4.3 bn $1.2 bn
183 Kanghua Biological Sichuan Province, China $4.3 bn $104 mn
184 Yiling Pharma Hebei Province, China $4.3 bn $1 bn
185 NCPC Hebei Province, China $4.3 bn $1.5 bn
186 Abdi Ibrahim Turkey $4.2 bn $639 mn
187 Jinyu Bio-Tech Mongolia $4.2 bn $175 mn
188 CHEPLAPHARM Pomerania, Germany $4.2 bn $1.1 bn
189 Ultragenyx Bay Area, US $4.2 bn $159 mn
190 Allogene Bay Area, US $4.1 bn NA
191 Meiji Pharma Business Tokyo, Japan $4.1 bn $1.9 bn
192 Orifarm Copenhagen, Denmark $4 bn $1.1 bn
193 Pharmstandard Dolgoprudny, Russia $4 bn $1.1 bn
194 Grupo Bago Argentina $4 bn $1.1 bn
195 Apeloa Pharma Zhejiang Province, China $4 bn $1 bn
196 Polpharma Poland $3.9 bn $1 bn
197 Idorsia Basel, Switzerland $3.9 bn $72 mn
198 Oneness Biotech Taiwan $3.9 bn $1.4 mn
199 Hisun Pharma Zhejiang Province, China $3.8 bn $1.5 bn
200 Halozyme San Diego, US $3.8 bn $180 mn
201 IBSA Lugano, Switzerland $3.8 bn $572 mn
202 Celltrion Pharm South Korea $3.7 bn $152 mn
203 neuraxpharm Langenfeld, Germany $3.7 bn $566 mn
204 Hypera Sao Paolo, Brazil $3.7 bn $694 mn
205 Ipca Mumbai, India $3.7 bn $617 mn
206 Esteve Barcelona, Spain $3.7 bn $556 mn
207 Biohaven New York Area, US $3.7 bn $10 mn
208 Haisco Sichuan Province, China $3.7 bn $498 mn
209 Gedeon Richter Hungary $3.6 bn $1.7 bn
210 Relay Therapeutics Boston Area, US $3.6 bn $0 mn
211 Legend Biotech Jiangsu Province, China $3.6 bn $61 mn
212 Hanmi Pharm South Korea $3.6 bn $917 mn
213 Barakat Pharmaceutical Iran $3.6 bn $1 bn
214 Blueprint Medicines Boston Area, US $3.6 bn $75 mn
215 Allakos Bay Area, US $3.6 bn NA
216 ALK Copenhagen, Denmark $3.6 bn $505 mn
217 LG Life Sciences South Korea $3.6 bn $540 mn
218 JCR Ashiya, Japan $3.5 bn $230 mn
219 Eurofarma Sao Paolo, Brazil $3.5 bn $982 mn
220 Genexine South Korea $3.5 bn $4.1 mn
221 ROHTO Osaka, Japan $3.5 bn $1.7 bn
222 Besins Monaco $3.5 bn $531 mn
223 Amicus Therapeutics New York Area, US $3.5 bn $226 mn
224 Perrigo Rx Business Allegan, MI, US $3.5 bn $968 mn
225 Denali Therapeutics Bay Area, US $3.5 bn $27 mn
226 Kyoritsu Seiyaku Tokyo, Japan $3.5 bn $524 mn
227 Zentiva Czech Republic $3.4 bn $957 mn
228 Genus London, United Kingdom $3.4 bn $682 mn
229 Amneal New York Area, US $3.4 bn $1.7 bn
230 China Grand Pharma Hong Kong $3.4 bn $807 mn
231 FibroGen Bay Area, US $3.4 bn $108 mn
232 Vir Biotechnology Bay Area, US $3.4 bn $75 mn
233 Dermapharm Munich Area, Germany $3.4 bn $855 mn
234 Schrodinger Bangalore, India $3.4 bn $95 mn
235 Dompe Milan, Italy $3.3 bn $507 mn
236 Luoxin Pharma Shandong Province, China $3.3 bn $897 mn
237 MorphoSys Munich Area, Germany $3.3 bn $329 mn
238 Shafadarou Investment Iran $3.3 bn $906 mn
239 Norgine Netherlands $3.3 bn $494 mn
240 AnkeBio Anhui Province, China $3.3 bn $235 mn
241 Yuhan South Korea $3.2 bn $1.2 bn
242 Macleods Pharma Mumbai, India $3.2 bn $891 mn
243 PROBIOMED Mexico $3.2 bn $317 mn
244 Dr. Falk Pharma Freiburg im Breisgau, Germany $3.2 bn $485 mn
245 ChemoCentryx Bay Area, US $3.2 bn $76 mn
246 Arrowhead Pharma Los Angeles, US $3.2 bn $123 mn
247 Taisho Pharma Tokyo, Japan $3.2 bn $2.8 bn
248 Pars Darou Iran $3.2 bn $881 mn
249 China Meheco Group Beijing, China $3.2 bn $5.2 bn
250 China Biologic Products Beijing, China $3.1 bn $511 mn
251 Bridgebio Pharma Bay Area, US $3.1 bn $40 mn
252 LFB Paris, France $3.1 bn $472 mn
253 PTC Therapeutics New York Area, US $3.1 bn $311 mn
254 Immunovant New York Area, US $3.1 bn NA
255 lnsmed New York Area, US $3.1 bn $163 mn
256 Asahi Kasei Pharma Tokyo, Japan $3.1 bn NA
257 GC Pharma South Korea $3 bn $1.1 bn
258 BrightGene Bio Jiangsu Province, China $3 bn $84 mn
259 medac gmbh Wedel, Germany $2.9 bn $446 mn
260 3SBio Liaoning Province, China $2.9 bn $760 mn
261 Amoytop Biotech Fujian Province, China $2.9 bn $109 mn
262 United Therapeutics Silver Spring MD, US $2.9 bn $1.4 bn
263 GBT Bay Area, US $2.9 bn $47 mn
264 GW Pharmaceuticals Cambridge, UK $2.9 bn $441 mn
265 Arena Pharma San Diego, US $2.9 bn $4.6 mn
266 Alvogen New York Area, US $2.9 bn $800 mn
267 Prasco Mason, Ohio, US $2.9 bn $800 mn
268 Simcere Pharma Jiangsu Province, China $2.9 bn $800 mn
269 ADC Therapeutics Geneva, Switzerland $2.9 bn $0 mn
270 Axsome New York, NY $2.9 bn NA
271 BIOCAD St. Petersburg, Russia $2.9 bn $283 mn
272 Guojian Pharma Shanghai, China $2.8 bn $149 mn
273 KrKa Slovenia $2.8 bn $1.7 bn
274 Chipscreen Guangdong Province, China $2.8 bn $28 mn
275 Harmony Biosciences Philadelphia Area, US $2.8 bn $63 mn
276 Fate Therapeutics San Diego, US $2.8 bn $13 mn
277 Reata Pharma Irving, TX, US $2.8 bn $13 mn
278 Hisamitsu Tosu, Japan $2.8 bn $1.2 bn
279 China Medical System Guangdong Province, China $2.8 bn $880 mn
280 Biolab Sanus Pharma Sao Paolo, Brazil $2.8 bn $418 mn
281 Biolab Sanus Pharma Sao Paolo, Brazil $2.8 bn $418 mn
282 Mankind Pharma Delhi, India $2.8 bn $766 mn
283 Sawai Osaka, Japan $2.7 bn $1.6 bn
284 Jubilant Pharma Segment Noida, UP, India $2.7 bn $758 mn
285 TG Therapeutics New York Area, US $2.7 bn $0.1 mn
286 Ethypharm Paris, France $2.7 bn $413 mn
287 China TCM Holdings Hong Kong $2.7 bn $1.9 bn
288 Kowa Pharma Segment Tokyo, Japan $2.7 bn $1.3 bn
289 Alembic Ahmedabad, India $2.7 bn $661 mn
290 Alkermes Boston Area, US $2.7 bn $1.1 bn
291 Nektar Bay Area, US $2.7 bn $162 mn
292 Neopharm Ltd Israel $2.6 bn $400 mn
293 AoDong Medicine Jilin Province, China $2.6 bn $363 mn
294 Chase Sun Pharma Tianjin, China $2.6 bn $778 mn
295 Akeso Guangdong Province, China $2.6 bn $10 mn
296 Joincare Pharma Guangdong Province, China $2.6 bn $1.7 bn
297 Turning Point San Diego, US $2.6 bn NA
298 Pacira New York Area, US $2.6 bn $408 mn
299 Dendreon / Sanpower Los Angeles, US $2.6 bn $393 mn
300 Bio-Thera Solutions Guangdong Province, China $2.6 bn $7 mn
301 Zelgen Bio Anhui Province, China $2.6 bn NA
302 Jumpcan Pharma Jiangsu Province, China $2.6 bn $847 mn
303 Luye Pharma Shandong Province, China $2.5 bn $876 mn
304 Shuanglin Biopharma Guangdong Province, China $2.5 bn $133 mn
305 Pharmascience Quebec, Canada $2.5 bn $700 mn
306 Almirall Barcelona, Spain $2.5 bn $981 mn
307 Karo Pharma Sweden $2.5 bn $276 mn
308 Ocumension Jiangsu Province, China $2.5 bn $0.3 mn
309 Fudan-Zhangjiang Shanghai China $2.5 bn $123 mn
310 Emcure Mumbai, India $2.4 bn $673 mn
311 OPKO Health Miami, Florida, US $2.4 bn $965 mn
312 Seres Therapeutics Boston Area, US $2.4 bn $28 mn
313 Xianju Pharma Zhejiang Province, China $2.4 bn $512 mn
314 Tsumura Osaka, Japan $2.4 bn $1.1 bn
315 Boya Bio Jiangxi Province, China $2.4 bn $404 mn
316 Galapagos Belgium $2.4 bn $1.1 bn
317 Teijin Pharma Tokyo, Japan $2.3 bn $1.1 bn
318 Fidia Farma Abano Terme, Italy $2.3 bn $354 mn
319 Glenmark Mumbai, India $2.3 bn $1.4 bn
320 CytoDyn Seattle, US $2.3 bn NA
321 Sage Therapeutics Boston Area, US $2.3 bn $8.9 mn
322 Biocodex Paris, France $2.3 bn $350 mn
323 Helsinn Lugano, Switzerland $2.3 bn $350 mn
324 Deciphera Boston Area, US $2.3 bn $7.1 mn
325 Virbac Carros, France $2.3 bn $1 bn
326 Conba Pharma Zhejiang Province, China $2.3 bn $893 mn
327 BIAL Portugal $2.3 bn $345 mn
328 Zhejiang Medicine Zhejiang Province, China $2.3 bn $989 mn
329 Adamed Poland $2.3 bn $343 mn
330 ASK Pharm Jiangsu Province, China $2.2 bn $526 mn
331 Hile Bio-Technology Shanghai, China $2.2 bn $36 mn
332 China Animal Husbandry Beijing, China $2.2 bn $644 mn
333 bluebird bio Boston Area, US $2.2 bn $239 mn
334 Liomont Mexico $2.2 bn $600 mn
335 Stallergenes Greer London, United Kingdom $2.2 bn $326 mn
336 Haiyao Hainan Province, China $2.1 bn $298 mn
337 Bailing Group Pharma Guizhou, China $2.1 bn $393 mn
338 Aristo Pharma Berlin, Germany $2.1 bn $590 mn
339 Nhwa Pharma Jiangsu Province, China $2.1 bn $500 mn
340 Huvepharma Bulgaria $2.1 bn $320 mn
341 PharmaMar Madrid, Spain $2.1 bn $240 mn
342 Aimmune Therapeutics Bay Area, US $2.1 bn $0.5 mn
343 Xinbang Pharma Guizhou, China $2.1 bn $860 mn
344 Haohai Biotech Shanghai, China $2.1 bn NA
345 Myovant Sciences Bay Area, US $2 bn $33 mn
346 ROVI Madrid, Spain $2 bn $444 mn
347 SSY Group Hong Kong $2 bn $528 mn
348 Norbrook Laboratories Northern Ireland, UK $2 bn $305 mn
349 Intra-Cellular Therapies New York Area, US $2 bn $3 mn
350 lnovio Pharma Philadelphia Area, US $2 bn $2.7 mn
351 Mesoblast Melbourne, Australia $2 bn $32 mn
352 Micro Labs Bangalore, India $2 bn $558 mn
353 Cheezheng Tibetan Med Nyingchi, Tibet, China $2 bn $198 mn
354 Agios Boston Area, US $2 bn $185 mn
355 Kodiak Sciences Palo Alto, CA $1.9 bn NA
356 Taiji Group Sichuan Province, China $1.9 bn $1.5 bn
357 Revance Bay Area, US $1.9 bn $0.4 mn
358 Apellis Pharma Boston Area, US $1.9 bn NA
359 Natco Hyderabad, India $1.9 bn $262 mn
360 MSN Laboratories Hyderabad, India $1.9 bn $520 mn
361 Karuna Therapeutics Boston Area, US $1.9 bn NA
362 Sorrento Therapeutics San Diego, US $1.9 bn $35 mn
363 IGM Biosciences Bay Area, US $1.9 bn NA
364 Shyndec Shanghai, China $1.8 bn $1.7 bn
365 CK Life Sciences Hong Kong $1.8 bn $612 mn
366 Bukwang Pharma South Korea $1.8 bn $142 mn
367 Ironwood Pharma Boston Area, US $1.8 bn $426 mn
368 Advanz Pharma London, United Kingdom $1.8 bn $503 mn
369 Medochemie Cyprus $1.8 bn $500 mn
370 Brilliant Pharma Sichuan Province, China $1.8 bn $500 mn
371 Grupo Uriach Barcelona, Spain $1.8 bn $271 mn
372 Square Pharma Bangladesh $1.8 bn $545 mn
373 Acino Zurich, Switzerland $1.8 bn $495 mn
374 Zhongheng Group Guangxi Province, China $1.8 bn $530 mn
375 Ajanta Pharma Mumbai, India $1.8 bn $350 mn
376 Xencor Los Angeles, US $1.8 bn $70 mn
377 SL Pharm Hainan Province, China $1.7 bn $214 mn
378 Hisoar Pharma Zhejiang Province, China $1.7 bn $356 mn
379 Xiangxue Pharma Guangdong Province, China $1.7 bn $464 mn
380 Eidos Therapeutics Bay Area, US $1.7 bn $26 mn
381 ZBD Pharmaceutical Heilongjiang Province, China $1.7 bn $450 mn
382 IDT Biologika Dessau-Roillau, Germany $1.7 bn $259 mn
383 Siam Bioscience Thailand $1.7 bn $169 mn
384 JT Pharma / Torii Tokyo, Japan $1.7 bn $815 mn
385 Theramex London, United Kingdom $1.7 bn $258 mn
386 HIPRA Spain, Other $1.7 bn $256 mn
387 Zhongsheng Pharma Guangdong Province, China $1.7 bn $284 mn
388 Quantum Hi-Tech Guangdong Province, China $1.7 bn $195 mn
389 Biotest / Creat Group Berlin, Germany $1.7 bn $516 mn
390 Sebela Pharma Atlanta, US $1.7 bn $250 mn
391 Tecnoquimicas Colombia $1.6 bn $458 mn
392 Corcept Therapeutics Bay Area, US $1.6 bn $351 mn
393 SINQI Liaoning Province, China $1.6 bn $74 mn
394 Towa Pharma Osaka, Japan $1.6 bn $1.1 bn
395 Nichi-Iko Toyama, Japan $1.6 bn $1.7 bn
396 Kolmar Medicine Unit South Korea $1.6 bn $567 mn
397 Hugel South Korea $1.6 bn $162 mn
398 Alphamab Oncology Jiangsu Province, China $1.6 bn $1.4 mn
399 Aurinia Pharma Vancouver, Canada $1.6 bn $0.3 mn
400 AnGes Osaka, Japan $1.6 bn $1.5 mn
401 USV Mumbai, India $1.6 bn $446 mn
402 Arkopharma Lyon, France $1.6 bn $241 mn
403 Kimia Farma Sumatera Utara, Indonesia $1.6 bn $662 mn
404 Bavarian Nordic Copenhagen, Denmark $1.6 bn $226 mn
405 Dezhan Healthcare Beijing, China $1.6 bn $221 mn
406 SpringWorks New York Area, US $1.6 bn NA
407 Zixin Pharma Jilin Province, China $1.6 bn $65 mn
408 HanAll Biopharma South Korea $1.6 bn $82 mn
409 Cytokinetics Bay Area, US $1.6 bn $18 mn
410 Gebro Pharma Austria $1.6 bn $236 mn
411 Clinigen Northern UK $1.5 bn $624 mn
412 Revolution Medicines Bay Area, US $1.5 bn $46 mn
413 Isdin Barcelona, Spain $1.5 bn $232 mn
414 Laboratorio Elea Argentina $1.5 bn $232 mn
415 ALX Oncology Bay Area, US $1.5 bn $3.6 mn
416 Forma Therapeutics Boston Area, US $1.5 bn $10 mn
417 FujiFilm Pharma Tokyo, Japan $1.5 bn NA
418 Laboratorios Sanfer Mexico $1.5 bn NA
419 Sanovel Turkey $1.5 bn $227 mn
420 SPIMACO Mosadia, Saudi Arabia $1.5 bn $417 mn
421 Abiogen Pharma Pisa, Italy $1.5 bn $223 mn
422 Akcea Therapeutics Boston Area, US $1.5 bn $336 mn
423 uniQure Netherlands $1.5 bn $5.3 mn
424 Innocare Hong Kong $1.5 bn $0.1 mn
425 Microgen Moscow, Russia $1.5 bn $144 mn
426 Intercept Pharma New York Area, US $1.5 bn $283 mn
427 Zymeworks Vancouver, Canada $1.4 bn $30 mn
428 Sobhan Pharma Iran $1.4 bn $397 mn
429 Viela Bio Gaithersburg, MD, US $1.4 bn $30 mn
430 Bimeda Animal Health Ireland $1.4 bn $216 mn
431 Y-mAbs Therapeutics New York Area, US $1.4 bn NA
432 Northeast Pharma Shenyang Province, China $1.4 bn $1.1 bn
433 Sunflower Pharma Heilongjiang Province, China $1.4 bn $507 mn
434 Biological E. Hyderabad, India $1.4 bn $140 mn
435 Editas Medicine Boston Area, US $1.4 bn $32 mn
436 Cortexyme Bay Area, US $1.4 bn NA
437 Yungjin Pharm South Korea $1.4 bn $147 mn
438 Kymera Boston Area, US $1.4 bn NA
439 Lukang Pharma Shandong Province, China $1.4 bn $549 mn
440 AlloVir Boston Area, US $1.4 bn $0 mn
441 Hybio Pharma Guangdong Province, China $1.4 bn $85 mn
442 URSAPHARM Saarbrucken, Germany $1.4 bn $206 mn
443 Uniao Qufmica Sao Paolo, Brazil $1.4 bn $376 mn
444 HEC Pharma Guangdong Province, China $1.4 bn $741 mn
445 Zhongxin Pharma Tianjin, China $1.3 bn $955 mn
446 MacroGenics Rockville MD, US $1.3 bn $77 mn
447 Kern Pharma Barcelona, Spain $1.3 bn $368 mn
448 Medison Israel $1.3 bn $200 mn
449 Theravance Biopharma Bay Area, US $1.3 bn $76 mn
450 Cosmo Pharma Lugano, Switzerland $1.3 bn $75 mn
451 Nestle Pharma Ops Vevey, Switzerland $1.3 bn $288 mn
452 Cerevel Therapeutics Boston Area, US $1.3 bn NA
453 Atnahs London, United Kingdom $1.3 bn $360 mn
454 Compugen Israel $1.3 bn NA
455 Coherus Bay Area, US $1.3 bn $487 mn
456 Mersana Boston Area, US $1.3 bn $1.6 mn
457 II-Yang Pharm. South Korea $1.3 bn $270 mn
458 Kura Oncology San Diego, US $1.3 bn NA
459 Madrigal Pharma Philadelphia Area, US $1.3 bn NA
460 GNI Group Tokyo, Japan $1.3 bn $77 mn
461 KUP South Korea $1.2 bn $136 mn
462 Weiguang Biological Guangdong Province, China $1.2 bn $122 mn
463 Changshan Bio Hebei Province, China $1.2 bn $308 mn
464 Nordic Pharma Paris, France $1.2 bn $182 mn
465 Ringpu BioTech Hebei Province, China $1.2 bn $245 mn
466 Renata Bangladesh $1.2 bn $310 mn
467 Gloria Pharmaceuticals Heilongjiang Province, China $1.2 bn $527 mn
468 Zealand Pharma Copenhagen, Denmark $1.2 bn $38 mn
469 Medy-Tox South Korea $1.2 bn $151 mn
470 Beam Therapeutics Boston Area, US $1.2 bn NA mn
471 Ligand San Diego, US $1.2 bn $126 mn
472 Leadiant Biosciences Rome, Italy $1.2 bn $180 mn
473 Zhenghai Biotech Shandong Province, China $1.2 bn $39 mn
474 Reliance Life Sciences Mumbai, India $1.2 bn $116 mn
475 Nkarta Bay Area, US $1.2 bn $0 mn
476 GuangYuYuang Shaanxi Province, China $1.2 bn $156 mn
477 Mayinglong Pharma Hubei Province, China $1.2 bn $341 mn
478 Zeria Pharma Tokyo, Japan $1.2 bn $543 mn
479 Laboratoire Aguettant Lyon, France $1.2 bn $177 mn
480 Adaptimmune Oxford, UK $1.2 bn $2.2 mn
481 Duchesnay Quebec, Canada $1.2 bn $175 mn
482 Mezzion South Korea $1.2 bn $17 mn
483 Rocket Pharma New York Area, US $1.2 bn NA
484 Akero Therapeutics Bay Area, US $1.2 bn NA
485 Alvotech Iceland $1.2 bn NA
486 Kanion Pharma Jiangsu Province, China $1.1 bn $545 mn
487 Hansa BioPharma Lund, Sweden $1.1 bn $0.3 mn
488 Synthon Netherlands $1.1 bn $316 mn
489 Innoviva Bay Area, US $1.1 bn $299 mn
490 Heron Therapeutics San Diego, US $1.1 bn $125 mn
491 Athenex New York Area, US $1.1 bn $140 mn
492 SAIDAL Algeria $1.1 bn $313 mn
493 Faes Farma Madrid, Spain $1.1 bn $458 mn
494 VTR Bio-tech Guangdong Province, China $1.1 bn $298 mn
495 Helixsmith South Korea $1.1 bn $4.4 mn
496 Amarin New York Area, US $1.1 bn $545 mn
497 Haw Par Corporation Singapore $1.1 bn $130 mn
498 Sam Chun Dang Pharm South Korea $1.1 bn $152 mn
499 Rhythm Pharma Boston Area, US $1.1 bn NA
500 iTeos Therapeutics Boston Area, US $1.1 bn $0 mn
501 Strides Bangalore, India $1.1 bn $377 mn
502 Kyorin Tokyo, Japan $1.1 bn $1 bn
503 Kaken Pharma Tokyo, Japan $1.1 bn $788 mn
504 Epizyme Boston Area, US $1.1 bn $13 mn
505 Nurix Therapeutics Bay Area, US $1.1 bn $19 mn
506 Camurus Lund, Sweden $1.1 bn $22 mn
507 Arbor Pharma Atlanta, US $1.1 bn $300 mn
508 Stendhal Pharma Mexico $1.1 bn $300 mn
509 Chengdu Baiyu Sichuan Province, China $1.1 bn $300 mn
510 Pulike Biological Henan Province, China $1.1 bn $108 mn
511 Bharat Biotech Hyderabad, India $1.1 bn $106 mn
512 Phibro Animal Health New York Area, US $1.1 bn $800 mn
513 Vianex Greece $1.1 bn $297 mn
514 Mithra Belgium $1.1 bn $108 mn
515 LACER Barcelona, Spain $1.1 bn $162 mn
516 Mayoly Spindler Paris, France $1.1 bn $161 mn
517 Lummy Pharma Sichuan Province, China $1.1 bn $235 mn
518 DONGKOOK Pharma South Korea $1.1 bn $433 mn
519 TECNIMEDE Portugal $1 bn $290 mn
520 Oscotec South Korea $1 bn $15 mn
521 Eczacibasi Mac Sanayi Levent, Turkey $1 bn $157 mn
522 Eurocept Netherlands $1 bn $288 mn
523 IBI Aprilia, Italy $1 bn $288 mn
524 Science Sun Beijing, China $1 bn $161 mn
525 Cristalia Sao Paolo, Brazil $1 bn $287 mn
526 Pharmicell South Korea $1 bn $23 mn
527 Sanjin Guangxi Province, China $1 bn $226 mn
528 Pharmathen Netherlands $1 bn $285 mn
529 Precigen Germantown MD, US $1 bn $95 mn
530 KPC Yunnan Province, China $1 bn $1.1 bn
531 Jiuzhitang Hubei Province, China $1 bn $471 mn
532 C Labs Madrid, Spain $1 bn $283 mn
533 Dr. Kade Berlin, Germany $1 bn $154 mn
534 Generation Bio Boston Area, US $1 bn $0 mn
535 BioXcel Therapeutics New York Area, US $1 bn NA
536 Adimmune Taiwan $1 bn $53 mn
537 Cadila Pharma Ahmedabad, India $1 bn $280 mn
538 Sana Seattle, US $1 bn NA
539 AYUMI Pharmaceutical Tokyo, Japan $1 bn $239 mn
540 Adverum Biotechnologies Bay Area, US $1 bn $0.2 mn
541 Karyopharm Boston Area, US $999 mn $82 mn
542 Haixin Group Shanghai, China $998.3 mn $146 mn
543 Lantheus Boston Area, US $997.3 mn $331 mn
544 Zogenix Bay Area, US $994.7 mn $4.8 mn
545 Tris Pharma Monmouth Junction NJ, US $990 mn $150 mn
546 Zhejiang Int’l Group Zhejiang Province, China $989.3 mn $3.6 bn
547 Annexon Bay Area, US $988.4 mn $0 mn
548 Guanhao Biotech Guangdong Province, China $985.3 mn $61 mn
549 Clovis Oncology Colorado, U.S. $983.4 mn $159 mn
550 Bottu Morocco $981 mn $272 mn
551 NGM Biopharmaceuticals Bay Area, US $979.7 mn $96 mn
552 Normon Madrid, Spain $979.2 mn $272 mn
553 Zentalis Pharma New York Area, US $974 mn $0 mn
554 Pharscin Pharma Sichuan Province, China $971.8 mn $115 mn
555 Oncopeptides Sweden $970.7 mn NA
556 Huaren Pharma Shandong Province, China $968.4 mn $189 mn
557 Fudan Forward Shanghai, China $964.2 mn $139 mn
558 Wockhardt Mumbai, India $964.1 mn $359 mn
559 Yipinhong Pharma Guangdong Province, China $960.8 mn $214 mn
560 TerSera Therapeutics Chicago Area $957 mn $145 mn
561 Eris Lifesciences Limited Ahmedabad, India $956.1 mn $142 mn
562 Dexa Medica Medan City, Indonesia $951 mn NA
563 Avidity Biosciences San Diego, US $949.2 mn $4.9 mn
564 Tonghua Golden-Horse Jilin Province, China $943.7 mn $213 mn
565 Shandong Shanda Shandong Province, China $941.4 mn $257 mn
566 Sosei Tokyo, Japan $940.1 mn $66 mn
567 Beijing Beilu Pharma Beijing, China $937.2 mn $111 mn
568 Amphastar Pharma Los Angeles, US $936.9 mn $334 mn
569 Takata Pharmaceutical Saitama, Japan $936 mn NA
570 Tabuk Pharma Riyadh, Saudi Arabia $936 mn $260 mn
571 Omeros Seattle, US $935 mn $100 mn
572 Healios Tokyo, Japan $932.4 mn $2.3 mn
573 Nippon Kayaku Pharma Tokyo, Japan $928 mn $444mm
574 Kiniksa Pharma Boston Area, US $926.3 mn NA
575 Boston Scientific Pharma Boston Area, US $924 mn $140 mn
576 Renhe Jiangxi Province, China $921.5 mn $577 mn
577 Applied Molecular Transp Bay Area, US $920.5 mn $0 mn
578 Tai’an Tang Pharma Shanghai, China $918.6 mn $547 mn
579 Arcus Biosciences Bay Area, US $914.1 mn $15 mn
580 Arcturus Therapeutics San Diego, US $910.4 mn $11 mn
581 Vetoquinol Paris, France $906.1 mn $444 mn
582 JW Holdings South Korea $905.5 mn $618 mn
583 Esperion Ann Arbor, MI, US $904.9 mn $216 mn
584 Apsen Sao Paolo, Brazil $900 mn $250 mn
585 Dexcel Pharma Israel $900 mn $250 mn
586 Agenus Boston Area, US $897.9 mn $96 mn
587 J. B. Chemicals Mumbai, India $897.5 mn $245 mn
588 Jingxin Pharm Zhejiang Province, China $895.1 mn $485 mn
589 Intellia Therapeutics Boston Area, US $894.5 mn $50 mn
590 Mochida Tokyo, Japan $892.1 mn $952 mn
591 Osiris Columbia MD, US $888.3 mn $134 mn
592 SKK Tokyo, Japan $887.3 mn $424 mn
593 Stoke Therapeutics, Inc. Boston Area, US $887 mn NA
594 Ampharco U.S.A. Nhon Trach, Vietnam $885.5 mn $245 mn
595 Oxford BioMedica Oxford, UK $885.1 mn $81 mn
596 Shanghai Furen Shanghai, China $884.9 mn $529 mn
597 Binex South Korea $884.1 mn $107 mn
598 Daewoong South Korea $884 mn $890 mn
599 Zhendong Pharma Shanxi Province, China $881.9 mn $622 mn
600 Sangamo Therapeutics Bay Area, US $881.8 mn $111 mn
601 TaiMed Biologics Taiwan $878.8 mn $28 mn
602 PharmaEssentia Taiwan $877.2 mn $11 mn
603 Jiangzhong Pharma Jiangxi Province, China $870.6 mn $349 mn
604 Pharm-Sintez Moscow, Russia $865.8 mn $240 mn
605 Dong-A Socio South Korea $860 mn $659 mn
606 Jingfeng Pharma Shanghai China $858 mn $172 mn
607 Jiudian Pharma Changsha, China $846.8 mn $126 mn
608 Incepta Pharma Bangladesh $843.7 mn $234 mn
609 Black Diamond Tx Boston Area, US $842.4 mn NA
610 Immunocore Oxford, UK $839.4 mn NA
611 Bosnalijek Bosnia-Herzegovina $837.7 mn $232 mn
612 Bilim Pharmaceuticals Turkey $836.2 mn $232 mn
613 Qianhong Biopharma Jiangsu Province, China $835.6 mn $210 mn
614 Akorn Chicago Area $833 mn $682 mn
615 Supernus Rockville MD, US $832.6 mn $424 mn
616 Jinhe Biotech Liaoning Province, China $830.8 mn $254 mn
617 Repare Therapeutics Toronto, Canada $830.4 mn $0 mn
618 REGENXBIO Rockville MD, US $828.4 mn $60 mn
619 Poseida Therapeutics San Diego, US $828.2 mn $0 mn
620 Atara Biotherapeutics Bay Area, US $827.8 mn NA
621 Beijing Tong Ren Tang Hebei Province, China $825.3 mn $600 mn
622 Tong Ren Tang Tech Beijing, China $825.3 mn $600 mn
623 Lingrui Pharma Henan Province, China $824.3 mn $306 mn
624 Xinhua Pharm Shandong Province, China $823.7 mn $816 mn
625 Cstone Pharma Jiangsu Province, China $822.9 mn $3.2 mn
626 Chong Kun Dang Pharm South Korea $821.1 mn $662 mn
627 Yoshindo Toyama, Japan $817 mn $391 mn
628 Atea Pharma Boston Area, US $817 mn NA
629 SanBio Tokyo, Japan $814 mn $0.1 mn
630 Nihon Chouzai Generics Tokyo, Japan $808.8 mn $2.5 bn
631 Laboratoires Brothier Fontevraud-l’Abbaye, France $805.8 mn $223 mn
632 Bioiberica Barcelona, Spain $803.7 mn $223 mn
633 Arvinas New York Area, US $802 mn $46 mn
634 Jolly Pharmaceutical Zhejiang Province, China $801.4 mn $134 mn
635 Pharmaceutical Associates Washington DC Area $800 mn $100 mn
636 Collegium Pharmaceutical Boston Area, US $797.7 mn $301 mn
637 Komipharm International South Korea $797.6 mn $31 mn
638 Guidotti Pisa, Italy $797.1 mn $221 mn
639 AOP Orphan Austria $794.3 mn $120 mn
640 Zdrowie Poland $793 mn $220 mn
641 Farmigea Pisa, Italy $790.2 mn $119 mn
642 Vectura London, United Kingdom $784.2 mn $218 mn
643 Keros Therapeutics Boston Area, US $782.5 mn $5 mn
644 The GPO Thailand $779.7 mn $216 mn
645 Tolmar / Tecnofarma Colombia $778.8 mn $118 mn
646 Eusa Pharma London, United Kingdom $778.8 mn $87 mn
647 Ji Yao Holding Jilin Province, China $774 mn $9.5 bn
648 Laboratoire Renaudin Itxassou, France $772 mn $214 mn
649 Lannett Philadelphia Area, US $771.9 mn $545 mn
650 Yibai Pharmaceutical Guizhou, China $770 mn $456 mn
651 BioArctic Norway $768.9 mn $9.8 mn
652 Wohua Pharma Shandong Province, China $765.8 mn $131 mn
653 Vericel Boston Area, US $765.7 mn $116 mn
654 Havea Group Bouffere, France $764.6 mn $212 mn
655 Prati, Donaduzzi & Cia. Toledo, Brazil $763.2 mn $212 mn
656 Lionco Pharma Zhejiang Province, China $762.4 mn $180 mn
657 Innovis Pharma Greece $760.3 mn $211 mn
658 RAPT Therapeutics Bay Area, US $756.9 mn $2.2 mn
659 Farmak Kiev, Ukraine $756 mn $236 mn
660 Medis o.o.o. Llubjana, Slovenia $755.4 mn $114 mn
661 Retrophin San Diego, US $754.5 mn $187 mn
662 Kocak Farma Istanbul, Turkey $752.4 mn $209 mn
663 Clinuvel Pharma Zurich, Switzerland $751.1 mn $22 mn
664 VBI Vaccines Boston Area, US $749.5 mn $1.8 mn
665 Replimune Boston Area, US $745 mn NA
666 Pharming Netherlands $743.8 mn $202 mn
667 Valenta Pharma Moscow, Russia $743.4 mn $206 mn
668 Inhibrx San Diego, US $743.1 mn NA
669 Desitin Hamburg, Germany $742.5 mn $112 mn
670 CrystalGenomics South Korea $740.2 mn $77 mn
671 FDC Mumbai, India $739.3 mn $173 mn
672 Kai Bao Pharma Shanghai, China $739.1 mn $156 mn
673 Blau Farmaceutica Cotia, Brazil $738.7 mn $205 mn
674 Fatro Milan, Italy $735.9 mn $111 mn
675 Arcutis Biotherapeutics Los Angeles, US $735.7 mn NA
676 NantKwest Los Angeles, US $735.4 mn NA
677 Translate Bio Lexington, MA $734.3 mn $26 mn
678 SIFI Sicily, Italy $731.1 mn $203 mn
679 Liminal BioSciences Quebec, Canada $729.1 mn NA
680 Jiangsu Sihuan Bio Jiangsu Province, China $729 mn $68 mn
681 Geropharm Russia $727.2 mn $72 mn
682 Maruishi Pharma Osaka, Japan $726.3 mn $347 mn
683 Currax Pharma New York Area, US $726 mn $110 mn
684 Yabao Pharmaceutical Shanxi Province, China $722 mn $370 mn
685 Exela Pharma Lenoir, NC $720 mn $200 mn
686 Nippon Zoki Osaka, Japan $718.9 mn $199 mn
687 Hengkang Medical Sichuan Province, China $716.6 mn $437 mn
688 Senju Pharma Osaka, Japan $710.6 mn $401 mn
689 Phathom Pharma New York Area, US $710.4 mn NA
690 Cosunter Fujian Province, China $709.8 mn $52 mn
691 Farabi Pharma Iran $709.2 mn $197 mn
692 Teuto Goias, Brazil $705.6 mn $196 mn
693 Acme Pharmaceuticals Bangladesh $704.5 mn $195 mn
694 Julphar United Arab Emirates $703.8 mn $102 mn
695 AB Science Paris, France $703.1 mn $1.7 mn
696 Jinghua Pharma Jiangsu Province, China $698.9 mn $159 mn
697 Dicerna Pharma Boston Area, US $692.1 mn $89 mn
698 Boryung Pharma South Korea $689.9 mn $456 mn
699 Beximco Pharma Bangladesh $689.9 mn $295 mn
700 MiMedx Atlanta, US $687.8 mn $280 mn
701 Staidson Beijing, China $686.8 mn $68 mn
702 Emisphere Technologies New York Area, US $675.7 mn $1 mn
703 Konruns Pharma Beijing, China $673.8 mn $123 mn
704 Exir Pharmaceutical Iran $671 mn $186 mn
705 DOC Generici Milan, Italy $669.6 mn $186 mn
706 Radius Boston Area, US $669 mn $200 mn
707 SillaJen South Korea $667.8 mn $1.9 mn
708 Basilea Basel, Switzerland $667.6 mn $148 mn
709 Vaxart Bay Area, US $667.3 mn $7.7 mn
710 Pharmasyntez Irkutsk, Russia $666 mn $185 mn
711 Cisen Pharmaceutical Shandong Province, China $663 mn $539 mn
712 Tchaikapharma Bulgaria $662.3 mn NA
713 MedDay Pharma Paris, France $660 mn NA
714 Pharmacosmos Copenhagen, Denmark $660 mn $100 mn
715 Eumedica Belgium $660 mn $100 mn
716 Shilpa Bangalore, India $658.2 mn $128 mn
717 Alector Bay Area, US $655.1 mn $19 mn
718 Senhwa Taiwan $653.1 mn NA
719 Dr. August Wolff Bielefield, Germany $649.5 mn $98 mn
720 Cellectis Paris, France $648.2 mn $73 mn
721 Kissei Matsumoto, Japan $647.1 mn $586 mn
722 SPARC Mumbai, India $644.4 mn $32 mn
723 Nobel Turkey $644.4 mn $179 mn
724 Indofarma Indonesia $642.9 mn $99 mn
725 Medigen Vaccine Taiwan $639.9 mn NA
726 Flexion Therapeutics Boston Area, US $639.8 mn $81 mn
727 Laboratoires Genevrier Lyon, France $639.4 mn $96 mn
728 Kadmon New York Area, US $632.1 mn $11 mn
729 Mayne Pharma Melbourne, Australia $624.6 mn $315 mn
730 Morphic Therapeutics Boston Area, US $622.4 mn $18 mn
731 Ozon Pharmaceuticals Russia $622 mn $172 mn
732 OBI Pharma Taiwan $617.4 mn $2 mn
733 Albireo Pharma Boston Area, US $616.9 mn $11 mn
734 Sinovac Beijing, China $615 mn $213 mn
735 Krystal Biotech Pittsburgh Area, US $614.6 mn NA
736 Provention Bio, Inc. New York Area, US $614 mn NA
737 ZENOAQ Tokyo, Japan $612.3 mn $293 mn
738 Alora Pharma Atlanta, US $612 mn $170 mn
739 Pliant Therapeutics Bay Area, US $608.7 mn $89 mn
740 Sciclone Shanghai, China $605 mn NA
741 Dynavax Bay Area, US $604.1 mn $34 mn
742 Handok South Korea $602.5 mn $405 mn
743 BioCryst North Carolina, US $602.3 mn $49 mn
744 Weixinkang Medicine Lhasa, Tibet, China $601.2 mn $95 mn
745 PKU HealthCare Corp. Sichuan Province, China $600.2 mn $311 mn
746 Inozyme Pharma Boston Area, US $597.4 mn $0 mn
747 Protagonist Therapeutics Bay Area, US $594.4 mn $16 mn
748 HRA Pharma New York Area, US $594 mn $90 mn
749 Molecular Templates Austin, Texas $592.7 mn $20 mn
750 Boiron Lyon, France $590.4 mn $623 mn
751 Nephron Pharma West Columbia, SC $589.3 mn $163 mn
752 CCM Duopharma Biotech Malaysia $586.4 mn $135 mn
753 Hiteck Biological Pharma Wuhan, China $585.7 mn $69 mn
754 Deva Holding Turkey $585.4 mn $230 mn
755 Laboraoires Majorelle Paris, France $583.2 mn $30 mn
756 SOHO Global Healthcare Indonesia $578.8 mn
757 Teikoku Senyaku Higashikagawa, Japan $576.8 mn $276 mn
758 Alliance Pharma London, United Kingdom $571.8 mn $162 mn
759 Caplin Point Laboratories Chennai, India $568.7 mn $120 mn
760 Nativa Russia $567.3 mn $157 mn
761 Cara Therapeutics New York Area, US $565.9 mn $24 mn
762 Grupo Medinfar Portugal $565.4 mn $157 mn
763 Gongwin Biopharm Taiwan $564.9 mn NA
764 Cassiopea S.p.A. Milan, Italy $564.7 mn $0.7 mn
765 Bath ASU London, United Kingdom $564.5 mn $156 mn
766 Frequency Therapeutics Boston Area, US $563.9 mn $44 mn
767 Foci Pharmaceutical Gansu Province, China $562.6 mn $91 mn
768 DEMO Greece $561.5 mn $155 mn
769 Newbridge Pharma United Arab Emirates $561 mn $85 mn
770 Inibsa Barcelona, Spain $560.6 mn $155 mn
771 Taloph Henan Province, China $559 mn $193 mn
772 Famar Greece $557.3 mn $154 mn
773 Akouos Therapeutics Boston Area, US $557.1 mn $0 mn
774 TTY Biopharm Taiwan $555.9 mn $144 mn
775 Amryt Pharma Ireland $554.4 mn NA
776 Intersect ENT Bay Area, US $552.9 mn $85 mn
777 HAL Allergy Netherlands $552.4 mn $83 mn
778 Hansen Pharm Hubei Province, China $551.2 mn $110 mn
779 Biosidus Argentina $551 mn $54 mn
780 Northwest Bio Bethesda MD, US $548 mn $2 mn
781 Farmfirma Soteks Russia $544.6 mn $151 mn
782 Jianmin Group Hubei Province, China $542.5 mn $304 mn
783 Cau Technology Guangdong Province, China $541.9 mn $7.6 mn
784 WAVE Life Sciences Boston Area, US $541.1 mn $12 mn
785 Elpen Pharma Greece $540 mn $150 mn
786 Petrovax Russia $538.5 mn $149 mn
787 Autolus Therapeutics London, United Kingdom $537.7 mn $1.2 mn
788 Berlin Pharma Thailand $536.4 mn $149 mn
789 Recursion Pharma Salt City, Utah $529 mn NA
790 Saol Therapeutics Atlanta, US $528 mn $80 mn
791 Sito Bio Shandong Province, China $527.8 mn $124 mn
792 TaiGen Taiwan $526.2 mn $0.7 mn
793 Taiwan Biotech Taiwan $525.4 mn $145 mn
794 ImmunoGen Boston Area, US $525 mn $86 mn
795 Kyowa Pharmaceutical Osaka, Japan $525 million $230 mm
796 JGL Croatia $523.5 mn $145 mn
797 Lepu Bio Shanghai, China $523 mn NA
798 Honz Pharma Guangdong Province, China $521.8 mn $127 mn
799 Getz Pharma Pakistan $520.2 mn $144 mn
800 ANI Pharmaceuticals Minnesota, US $519.6 mn $197 mn
801 PharmaResearch Prod. South Korea $519.4 mn $76 mn
802 Yakult Pharma Segment Tokyo, Japan $519 mn NA
803 Freeline Therapeutics Stevenage, UK $518.3 mn $0 mn
804 Gossamer Bio San Diego, US $516.6 mn NA
805 Shenqi Pharmaceutical Guizhou, China $516.2 mn $262 mn
806 DHG Pharma Can Tho, Vietnam $516 mn $164 mn
807 Valneva Lyon, France $515.7 mn $134 mn
808 Ocular Therapeutix Boston Area, US $515.5 mn $7.2 mn
809 Hua Medicine Hong Kong $513 mn $3.1 mn
810 Enanta Boston Area, US $512.2 mn $150 mn
811 Rana Pharm South Korea $511.2 mn $142 mn
812 Cosar Pharmaceutical Iran $511.2 mn $142 mn
813 Aerie Pharmaceuticals North Carolina, US $510.2 mn $81 mn
814 Organogenesis Boston Area, US $508.1 mn $269 mn
815 TherapeuticsMD Boca Raton, FL $506.2 mn $62 mn
816 Consilient Health Ireland $506.2 mn $76 mn
817 Huons South Korea $505.1 mn $402 mn
818 SIGA Technologies New York Area, US $504.9 mn $55 mn
819 Syndax Pharmaceuticals Boston Area, US $504.6 mn $1.5 mn
820 Corium Bay Area, US $504 mn NA
821 Genor Biopharma Shanghai, China $503 million NA
822 IE Ulagay Turkey $501.4 mn $139 mn
823 Ambiopharm North August, SC, US $500 mn NA
824 Odin Pharmaceuticals Somerset NJ $500 mn $80 mn
825 NKMax Los Angeles, US $496.5 mn $7.6 mn
826 Teyi Pharmaceutical Group Guangdong Province, China $496 mn $105 mn
827 Jeil South Korea $495.1 mn $624 mn
828 TCR2 Therapeutics Boston Area, US $494.3 mn NA
829 Celon Pharma Poland $494.2 mn $25 mn
830 Hicin Jiangsu Province, China $493.8 mn $119 mn
831 Fengyuan Pharmaceutical Anhui Province, China $493.3 mn $459 mn
832 kaleo Richmond, Virginia $492.2 mn $125 mn
833 Aprea Therapeutics, Inc. Boston Area, US $491.8 mn NA
834 AMAG Pharma Boston Area, US $489.7 mn $297 mn
835 Aprogen Pharmaceuticals South Korea $486.4 mn $45 mn
836 Pandion Therapeutics Boston Area, US $484.9 mn $4.9 mn
837 Green Cross Cell South Korea $483 mn $31 mn
838 Arterium Kiev, Ukraine $482.7 mn $134 mn
839 Sopharma Bulgaria $480.7 mn $775 mn
840 OM Pharm Zurich, Switzerland $478 mn $101 mn
841 ZIOPHARM Oncology Boston Area, US $476.2 mn NA
842 ASKA Pharmaceutical Tokyo, Japan $474.7 mn $484 mn
843 Dongwha Pharm South Korea $473.6 mn $245 mn
844 Relmada Therapeutics New York, NY $471.4 mn NA
845 YungShin Global Taiwan $470.4 mn $280 mn
846 Vertice Pharma New York Area, US $468 mn $130 mn
847 Farmac-Zabban Bologna, Italy $467.8 mn $129 mn
848 MannKind Los Angeles, US $466 mn $61 mn
849 Ansun Biopharma San Diego, US $466 million NA
850 BiondVax Pharmaceuticals Israel $464.8 mn NA
851 Amlyx Boston Area, US $464 million NA
852 XOMA Bay Area, US $463.8 mn $10 mn
853 Codupha Ho Chi Minh, Vietnam $463.6 mn $128 mn
854 Yatai Pharma Zhejiang Province, China $463.4 mn $55 mn
855 SERB Belgium $463.3 mn $70 mn
856 FangSheng Pharma Hubei Province, China $462.8 mn $160 mn
857 CMG Pharma South Korea $462.5 mn $49 mn
858 Romark Tampa, FL $462 mn $70 mn
859 Reig Jofre Barcelona, Spain $461.8 mn $257 mn
860 Poly Pharmaceuticals Huntsville, AL $460.8 mn $128 mn
861 Lianhuan Pharma Jiangsu Province, China $459.7 mn $191 mn
862 Eagle Pharma New York Area, US $458.4 mn $177 mn
863 Odonate Therapeutics San Diego, US $456.5 mn NA
864 Qianjin Pharmaceutical Hubei Province, China $455.6 mn $497 mn
865 Cue Biopharma Boston Area, US $454.7 mn $4 mn
866 Longjin Pharmaceutical Yunnan Province, China $452.3 mn $34 mn
867 ORIC Pharma Bay Area, US $451.9 mn NA
868 Jiaying Pharmaceutical Guangdong Province, China $451.6 mn $69 mn
869 Hanlim South Korea $448.5 mn $124 mn
870 Daito Pharmaceutical Toyama, Japan $448.3 mn $417 mn
871 Guangji Pharmaceutical Hubei Province, China $448.2 mn $100 mn
872 Silence Therapeutics London, United Kingdom $447.1 mn $1.7 mn
873 Bristol Laboratories London, United Kingdom $445.2 mn $123 mn
874 Pengqi Technology Devp Shanghai China $443.1 mn $121 mn
875 Soria Natural Garray, Spain $442.7 mn $122 mn
876 MIP Group Blieskastel, Germany $442.4 mn $122 mn
877 Osmotica New York Area, US $440.1 mn $211 mn
878 SALVAT Barcelona, Spain $440 mn $66 mn
879 Jacobson Pharma Hong Kong $439.4 mn $202 mn
880 Indivior Richmond, Virginia $439.4 mn $634 mn
881 Eutilex South Korea $439.1 mn $0.8 mn
882 89bio Bay Area, US $439.1 mn NA
883 Aptose Biosciences Toronto Area, Canada $438.8 mn NA
884 Pharma Foods International Kyoto, Japan $437.7 mn $145 mn
885 Anika Therapeutics Boston Area, US $437 mn $125 mn
886 Starpharma Melbourne, Australia $435.8 mn $4.5 mn
887 Lisheng Pharma Hebei Province, China $435.1 mn $194 mn
888 Taihe Health Technology Sichuan Province, China $433.3 mn $101 mn
889 Farma de Colombia SAS Colombia $432 mn $120 mn
890 Brainstorm Cell Tx New York Area, US $431.7 mn NA
891 RedHill Biopharma Tel-Aviv, Israel $431.1 mn $24 mn
892 Spectrum Las Vegas, NV $430.1 mn NA
893 Anterogen South Korea $428.6 mn $3.4 mn
894 Tricida Bay Area, US $428 mn NA
895 Panlong Pharmaceutical Shangluo, China $426 mn $64 mn
896 Alter Pharma Belgium $424.8 mn $118 mn
897 Passage Bio, Inc. Philadelphia Area, US $423.4 mn NA
898 Molecular Partners Zurich, Switzerland $422.3 mn $15 mn
899 Caregen South Korea $422.2 mn $53 mn
900 Ferndale Pharma Group Michigan, US $421.7 mn $63 mn
901 Franco-Indian (FIPPL) Mumbai, India $420.7 mn $116 mn
902 La borate Pharmaceuticals Haryana, India $420.1 mn $116 mn
903 Qianjiang Pharmaceutical Hubei Province, China $418.5 mn $111 mn
904 Highland Therapeutics Toronto Area, Canada $418 mn NA
905 Molteni Florence, Italy $417.7 mn $63 mn
906 TOA EIYO Tokyo, Japan $416 mn $131 mn
907 Syros Pharma Boston Area, US $414.3 mn $6.6 mn
908 Medigen Taiwan $413.1 mn $18 mn
909 Beyond Spring Pharma New York Area, US $412.5 mn NA
910 Theragen Etex South Korea $412.4 mn $114 mn
911 Calliditas Therapeutics Sweden $412.2 mn $5 mn
912 Vyera Therapeutics New York Area, US $411.8 mn $62 mn
913 Neoleukin Therapeutics Seattle, US $411.6 mn NA
914 Daewon Pharm South Korea $410.9 mn $265 mn
915 HLS Therapeutics Toronto Area, Canada $409.8 mn $53 mn
916 Puma Biotechnology Los Angeles, US $409.2 mn $241 mn
917 Kymab Cambridge, UK $408.5 mn NA
918 Seikagaku Tokyo, Japan $408.2 mn $259 mn
919 Diachem Bergamo, Italy $408.2 mn $113 mn
920 Adcock Ingram South Africa $407.5 mn $423 mn
921 Applied Therapeutics, Inc. New York Area, US $404.7 mn NA
922 Instituto Vital Brazil Rio de Janeiro, Brazil $403.3 mn $112 mn
923 iNtRON Biotechnology South Korea $403.2 mn $25 mn
924 Moehs Barcelona, Spain $401.8 mn $111 mn
925 US WorldMeds Louisville, KY, US $400 mn NA
926 Yisheng Pharma Jilin Province, China $398.9 mn $128 mn
927 BioDelivery Sciences North Carolina, US $397.8 mn $136 mn
928 Cosette Pharma New York Area, US $396 mn $110 mn
929 Aft Pharm New Zealand $395.4 mn $62 mn
930 Synmosa Biopharma Taiwan $393.9 mn $97 mn
931 Ardelyx Bay Area, US $391.9 mn $8.3 mn
932 Bluefish Pharmaceuticals Stockholm, Sweden $391.7 mn $108 mn
933 Furui Beijing, China $390.6 mn $114 mn
934 G1 Therapeutics North Carolina, US $390.4 mn $2.1 mn
935 Blue Pharma-Industria Portugal $389.2 mn $108 mn
936 Belupo Croatia $385.2 mn $107 mn
937 Ohara Pharma Tokyo, Japan $384.3 mn $183 mn
938 Mirum Pharmaceuticals Bay Area, US $384.2 mn NA
939 Cellular Biomedicine Bay Area, US $382.3 mn $0.2 mn
940 Sihuan Pharma Beijing, China $382.2 mn $323 mn
941 Neutec Ilac Turkey $378.3 mn $105 mn
942 Ildong Pharmaceutical South Korea $378 mn $467 mn
943 AC Immune Lausanne, Switzerland $376.4 mn $50 mn
944 Lee’s Pharmaceutical Hong Kong $376 mn $150 mn
945 VIVUS Bay Area, US $375.5 mn $56 mn
946 Scholar Rock Holding Boston Area, US $371.4 mn $21 mn
947 Therabel Pharma Netherlands $370 mn NA
948 Humanigen Bay Area, US $369.6 mn NA
949 Fortress Biotech New York Area, US $369.5 mn $43 mn
950 Savior Lifetec Taiwan $368.7 mn $52 mn
951 Assembly Biosciences Bay Area, US $368.2 mn $52 mn
952 Rigel Pharmaceuticals Bay Area, US $367.8 mn $108 mn
953 Kala Pharmaceuticals Boston Area, US $367.7 mn $4.5 mn
954 Materia Medica Moscow, Russia $367.2 mn $102 mn
955 Fuji Pharma Tokyo, Japan $365.8 mn $314 mn
956 Ovid Therapeutics New York Area, US $364.7 mn NA
957 TransMedics Group Andover, MA $363.1 mn $24 mn
958 Kintor Pharma Jiangsu Province, China $362.5 mn $0 mn
959 Urovant Sciences Irvine, CA $362.3 mn $0 mn
960 Darnitsa Ukraine $360 mn $100 mn
961 MS Pharma – El Kendi Algeria $360 mn $100 mn
962 Ascendis Health South Africa $359.3 mn $427 mn
963 Kolon Life Sciences South Korea $358.9 mn $128 mn
964 Nissin Tendo, Japan $358.1 mn $171 mn
965 Indoco Mumbai, India $357.3 mn $149 mn
966 Atreca Bay Area, US $357 mn NA
967 Alium Group Russia $355.6 mn $98 mn
968 The Searle Company Pakistan $355.3 mn $98 mn
969 Kwang Dong Pharma South Korea $353.9 mn $1 bn
970 Jinling Pharma Jiangsu Province, China $353.7 mn $338 mn
971 Verona Pharma London, United Kingdom $351.5 mn NA
972 EIPICO Egypt $351.5 mn $192 mn
973 HNSP Hainan Province, China $350.6 mn $40 mn
974 AVROBIO Boston Area, US $350.5 mn NA
975 Checkmate Pharma Boston Area, US $350.4 mn NA
976 Xinguan Pharmaceutical Zhejiang Province, China $350.2 mn $39 mn
977 Flynn Pharma London, United Kingdom $349.9 mn $59 mn
978 Tanvex Taiwan $349.2 mn NA
979 C&Y Group Shanxi Province, China $347.7 mn $137 mn
980 ACME Laboratories Bangladesh $347.5 mn $213 mn
981 TAEJOON PHARM South Korea $347 mn $96 mn
982 Farmabase Jaguariuna, Brazil $346.5 mn $52 mn
983 Xbiotech Austin, TX, US $345.1 mn $28 mn
984 Apex Healthcare Malaysia $343.6 mn $167 mn
985 Oyster Point Pharma Princeton, NJ, US $342.2 mn NA
986 Athersys, Inc. Cleveland, Ohio $341.7 mn $0 mn
987 Paratek Boston Area, US $341.7 mn $30 mn
988 PBF Taiwan $340.3 mn $50 mn
989 Grupo Azevedos Portugal $339.8 mn $94 mn
990 Centaur Pharma Mumbai, India $338.8 mn $94 mn
991 SOTH EMA Morocco $338.4 mn $178 mn
992 Orchard Therapeutics London, United Kingdom $338.4 mn $3.1 mn
993 Cantargia Lund, Sweden $338.4 mn NA
994 Tiansheng Pharma Jiangsu Province, China $337.8 mn $199 mn
995 Tiziana Life Sciences London, United Kingdom $337.3 mn NA
996 Aestura South Korea $336.9 mn $93 mn
997 UroGen Pharma New York Area, US $336.5 mn $0.3 mn
998 Telix Melbourne, Australia $336.4 mn NA
999 China Chemical & Pharma Taiwan $336 mn $272 mn
1000 Shapuaisi Pharma Zhejiang Province, China $335.5 mn $55 mn

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